Ciprodex ear drops is a prescription medicine used to treat middle ear infections inside the ear (also called otitis media), and infections of the outer ear canal (also called otitis externa). Ciprodex package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. CIPRODEX is a prescription medicine used in the ear only (otic use) that contains 2 medicines, a quinolone antibiotic medicine called ciprofloxacin and a corticosteroid medicine called dexamethasone. Find patient medical information for Ciprofloxacin/Dexamethasone (Ciprodex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings CIPRODEX OTIC prescription and dosage information for physicians and health care professionals. Pharmacology, adverse reactions, warnings, and CIPRODEX OTICside effects. Ciprodex is an ear drop suspension that contains ciprofloxacin (a fluoroquinolone antibiotic) and dexamethasone (a corticosteroid). It's used to treat middle and outer ear infections in people ages 6 years and older. Ciprodex combines an antibiotic (ciprofloxacin) with a steroid (dexamethasone). While the antibiotic kills bacteria causing the infection, the steroid reduces inflammation, pain, and swelling.